The perfect Oxford shirt for tech users

This Summer Oxford shirt from VoyVoy is perfect for the gadget user. ?While it looks like a typical Oxford, this shirt has a couple of extra features. ?When you use the tail of ?this shirt for cleaning your glasses or touch screens, you’ll have a microfiber cleaning patch to make cleaning easier and possible less [...]

Source: http://the-gadgeteer.com/2013/06/21/the-perfect-oxford-shirt-for-tech-users/

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Apparently Google is internally testing a service called "Google Mine" that lets you index all your

Apparently Google is internally testing a service called "Google Mine" that lets you index all your crap on Google+. Like, the physical items you own. You'll be able to share them on Google+ and set statuses for them like "given away," "gift recieved" or "had in the past." Of course Google would like to know that.

Source: http://gizmodo.com/apparently-google-is-internally-testing-a-service-calle-531459420

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Mo. woman charged in antifreeze poisoning deaths

SPRINGFIELD, Mo. (AP) ? A southwest Missouri woman is charged with using antifreeze to fatally poison her husband and son and attempt to kill her daughter over a 14-month period.

Fifty-one-year-old Diane Staudte of Springfield was charged Friday with two counts of first-degree murder, one count of first-degree assault and one count of armed criminal action. She is being held without bond. It isn't immediately clear if she has an attorney.

The probable cause statement says authorities received an anonymous tip earlier this month.

The statement says Staudte admitted under questioning to killing her husband, 61-year-old Mark Staudte, in April 2012 and her son, 26-year-old Shawn Staudte, in September.

The statement also says she admitted poisoning her daughter, 24-year-old Sarah Staudte, this month. She survived.

Source: http://news.yahoo.com/mo-woman-charged-antifreeze-poisoning-deaths-171144432.html

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Realistic 3-d tumor created through tissue engineering using silk scaffolds

June 20, 2013 ? A team of NUS researchers from the Departments of Bioengineering and Orthopaedic Surgery has developed a highly realistic three-dimensional (3-D) tumour model. As it replicates the conditions in the body, it is able to track the effectiveness and progress of drug therapy. Their model has the potential to be a more effective method for studying tumours than in-vitro and even in-vivo methods.

The team comprised Professor James Goh, Associate Professor Toh Siew Lok and Dr Pamela Tan from the Department of Bioengineering at NUS Faculty of Engineering, and Associate Professor Saminathan Suresh Nathan from the Department of Orthopaedic Surgery at the NUS Yong Loo Lin School of Medicine, who carried out their study using osteosarcoma, which is the most prevalent form of paediatric primary bone cancer.

Reconstructing tumours in the laboratory has been a hot topic for research as current methods of testing have not been sufficient to yield concrete results.

Dr Tan, who has been researching on the 3-D model for her PhD thesis, said: "Despite the urgent need to develop cancer therapeutics, little progress has been made due to the lack of good pre-clinical drug testing models. Current laboratory drug testing methods yield results that differ largely from animal testing because of the use of 2-D cell culture systems which cannot replicate the 3-D properties of the tumour tissue."

In in-vitro testing, cell culture systems are largely 2-D, hence, lack the structural features of the 3-D microenvironment. On the other hand, it is not feasible to carry out large-scale molecular biology research using in-vivo experiments. Furthermore, society has become increasingly concerned about the use of animals in experimentation.

Prof Goh said that tissue engineering, a major focus of study at the Department of Bioengineering, can help bridge these gaps, thereby establishing a more physiological 3-D in-vitro model. The team made use of techniques from tissue engineering to fabricate the 3-D tumour model and reconstructed the tumour tissue into factors and cell types in order to form a clinically relevant tumour.

The team decided to use silk to fabricate the scaffolds onto which the osteosarcoma cells were grown because it has been demonstrated to have excellent properties for cell attachment and growth.

Their 3-D tumour construct gives results that are much closer to those obtained from in-vivo studies, as compared to 2-D in-vitro studies. When chemotherapeutic drugs (which target aggressively growing cells) were tested on the 3-D tumour constructs, their effectiveness in killing cancer cells was greatly reduced, compared to testing the same drugs using the standard 2-D system. Moreover, the therapeutic doses found using the 3-D tumour constructs was within those measured in mice, indicating that the constructs have the potential to help bridge the gap between laboratory and animal testing, in order to improve the yield and quality of chemotherapeutic drug screening.

This is also the first time that a realistic 3-D tumour has been constructed in a laboratory using silk scaffolds in a pressurised bioreactor. Their 3-D bioreactor tumour model was able to express markers that indicate the ability of a tumour to initiate blood vessel growth at levels almost identical to that of the mouse model. The tumour constructs also responded to drugs that prevent blood vessel formation in a manner similar to that observed clinically.

"Our model also makes it possible to study how tumour cells interact with cells of the surrounding tissue, which results in more aggressive tumour behaviour," added Dr Tan.

The team has been developing the concept of the tumour microenvironment as an important determinant of tumour behaviour over the last 10 years.

Said Assoc Prof Nathan, "Dr Tan's recent contribution has shed remarkable insight into mechanisms of angiogenesis that were previously taken for granted and may now have to be re-addressed. Clinically this will have significant bearing on other drugs as well."

"We will in future be expanding our findings to other cancers and incorporating other aspects of the tumour microenvironment like oxygen levels within the system to ultimately create a platform for testing that could save much in downstream applications of experimental drugs," he added.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_technology/~3/j2xruZ4bzBI/130620071446.htm

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Source: http://today.msnbc.msn.com/id/3208047/device/rss/rss.xml

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Lavrov: Russian rebels will pose no risk at Sochi

ST. PETERSBURG, Russia (AP) ? Security agencies will make sure Russians fighting alongside rebels in Syria don't pose a threat to the 2014 Winter Games in Sochi, the foreign minister said Friday.

Sergey Lavrov said in an interview that the potential threat of them coming home to launch attacks "would be taken into account very seriously."

Lavrov said Moscow and Washington will cooperate on ensuring security for the Sochi Olympics, "making sure that the potentials of respective services and agencies of Russia and the United States are brought together to make the preparations more efficient."

He refused to elaborate on what specific steps will be taken.

Some observers have voiced concern that Islamic militants from Russia who have fought together with Syrian rebels could return home and try to take revenge against Russia for its support of Syrian President Bashar Assad. The chief of Russia's top security agency has said that about 200 Russians have joined the Syrian rebels, and acknowledged they could be a threat when they return.

Lavrov said nationals of European countries also have joined the rebels in Syria, and may pose a similar challenge to their home countries.

"This is not only relevant in the context of the Olympics, it's also relevant in the context of day-to-day life of entire Europe, the United States and other countries," he told The Associated Press and the Bloomberg news agency. "When this war is over ... these guys wouldn't be busy and they might look for some engagement" in the countries where they are citizens.

Russian officials have said that they have taken all necessary precautions to ensure the 2014 Winter Games in the Black Sea resort of Sochi will be "the safest Olympics in history." But security experts have pointed at an Islamic insurgency across the North Caucasus mountains that tower over Sochi, saying it could put President Vladimir Putin's pet project at risk.

The elder of the two ethnic Chechen brothers from Russia who are accused of staging the Boston Marathon bombings spent six months last year in the restive Russian province of Dagestan, which lies about 500 kilometers (300 miles) east of Sochi. Russian investigators have been trying to determine whether he had contact with local Islamic militants.

Dagestan has become the epicenter of Islamic insurgency that has destabilized the North Caucasus, with rebels mounting daily attacks on police and other officials.

Lavrov sought to downplay the threat posed by militants in the Caucasus. "Terrorist attacks happen, they aren't as numerous as before, and the Russian security services are becoming much more efficient in not only fighting the terrorists but also in preventing terrorist attacks," he said.

Source: http://news.yahoo.com/lavrov-russian-rebels-pose-no-risk-sochi-181451831.html

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Adobe's Q2 Earnings Beat Street With $1.011B In Revenue, $0.36 EPS, 700K Paying Creative Cloud Subscribers

Adobe just reported earnings for its second financial quarter of 2013. The company reported revenue of $1.011 billion and non-GAAP operating income of $247.3 for an earnings per share of $0.36 (though diluted GAAP earnings were only $0.15). That's a little bit better than most analysts expected, especially with respect to the company's earnings per share.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Hv9VjuMwoWk/

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