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FILE - In this Oct. 8, 2011 file photo, from left, Prince Jackson, Prince Michael II "Blanket"Jackson and Paris Jackson arrive on stage at the Michael Forever the Tribute Concert, at the Millennium Stadium in Cardiff, Wales. Jurors hearing a civil case in Los Angeles filed by Jackson?s mother, Katherine Jackson, have heard numerous stories about the entertainer?s devotion to his children as expressed through extravagant birthday parties and secret family outings. The tender moments have been described throughout the trial, which concluded its eighth week on Friday, June 21, 2013. (AP Photo/Joel Ryan, file) *Editorial Use Only*
FILE - In this Oct. 8, 2011 file photo, from left, Prince Jackson, Prince Michael II "Blanket"Jackson and Paris Jackson arrive on stage at the Michael Forever the Tribute Concert, at the Millennium Stadium in Cardiff, Wales. Jurors hearing a civil case in Los Angeles filed by Jackson?s mother, Katherine Jackson, have heard numerous stories about the entertainer?s devotion to his children as expressed through extravagant birthday parties and secret family outings. The tender moments have been described throughout the trial, which concluded its eighth week on Friday, June 21, 2013. (AP Photo/Joel Ryan, file) *Editorial Use Only*
In this undated photo released by the LA Superior Court and presented as evidence, a 2009 message written by Paris Jackson about her father, Michael Jackson, is seen on a chalkboard that was placed in the kitchen of the singer?s rented mansion in Los Angeles. The message remained on the board on the day Jackson died in June 2009, and was described to a jury hearing a case in Los Angeles filed by Jackson?s mother by the singer?s chef, Kai Chase, during testimony on Tuesday, June 18, 2013. (AP Photo/LA Superior Court)
FILE - In this May 27, 2006 file photo, Michael Jackson smiles during a press conference of the MTV Video Music Awards Japan 2006 in Tokyo. The U.S. entertainer was awarded a Legend Award at the ceremony. Jurors hearing a civil case in Los Angeles filed by Jackson?s mother, Katherine Jackson, have heard numerous stories about the entertainer?s devotion to his children as expressed through extravagant birthday parties and secret family outings. The tender moments have been described throughout the trial, which concluded its eighth week on Friday, June 21, 2013. (AP Photo/Koji Sasahara, File)
FILE - In this Jan. 25, 2006 file photo, Michael Jackson, center, wears an abaya, the traditional Arabic women's veil and all-covering gown, and holds the hand of one of his children, also veiled, as they walk toward their car behind a shopping mall, in Manama, Bahrain. Jackson, a reclusive resident of the Gulf island country since being cleared of child molestation charges, was accompanied by his sister, Janet, unseen, and two other children on the shopping outing. Jurors hearing a civil case in Los Angeles filed by Jackson?s mother, Katherine Jackson, have heard numerous stories about the entertainer?s devotion to his children as expressed through extravagant birthday parties and secret family outings. The tender moments have been described throughout the trial, which concluded its eighth week on Friday, June 21, 2013. (AP Photo/Hasan Jamali, File)
LOS ANGELES (AP) ? Courtrooms have supplied the epilogue to Michael Jackson's life. They've provided the forum where his debts have been settled, his final days dissected and his life depicted as a cautionary tale.
In nearly four years of court proceedings, two juries have watched Jackson come to life on video screens. They've watched him spin, dance, and then disappear. They've heard his voice, seen his handwriting and viewed photos of his lifeless body.
His role as a father has been described in little more than platitudes. Until now.
The jury hearing a civil case filed by the superstar's mother ? against AEG Live LLC, the promoter of Jackson's ill-fated concerts ? are experiencing details of a world previously held under lock and key. They've heard of extravagant birthday parties, secret family outings and the leg-clinging devotion of his children.
Jackson shielded the youngsters from the public eye, home-schooling them and often hiding their faces in public.
Away from the cameras, Jackson tried to create an environment of love, attention and special moments for his children, Michael Joseph "Prince" Jackson Jr., Paris-Michael Katherine Jackson and Prince Michael "Blanket" Jackson.
The following are some of some of the stories they've told. They present a portrait of Jackson as a father that outsiders never saw.
___
The final month of Jackson's life was a busy time. There were rehearsals for "This Is It," planning meetings and film shoots for a series of mini-movies that would precede some of his greatest hits at the London shows.
Jackson brought his children to the shoot for a "Smooth Criminal" video that culminated with Jackson leaping through a window while being shot at by Humphrey Bogart.
Alif Sankey, a backup dancer on the original video who was working on the comeback concerts, sat next to Paris during the shoot. The 11-year-old wanted to share a secret and opened up her purse.
It was filled with candy, Sankey recalled.
Jackson didn't want his children to eat sweets, and Paris asked Sankey to keep it quiet.
The dancer noticed something else inside the purse ? tiny picture frames with images of her father.
"Her purse was full of candy and pictures of Daddy."
___
Despite being home-schooled, there was no shortage of companions for Jackson's children.
Chef Kai Chase recalled numerous pets in the mansion that Jackson was renting while he prepared for his "This Is It" shows.
There was the talking bird, Siberia, who whistled at pretty women.
The children also had a chocolate Labrador named Kenya, whom Chase bought a cookbook for so she could bake him treats and a birthday cake. Two cats, named Katie and Thriller, also roamed the house.
During opening statements of the civil trial, some of the jury's first exposure to life in the Jackson home came from footage shot on a Christmas morning several years ago. Jackson's ode to his children, "You Are My Life" played as jurors watched a video of a Christmas morning from years ago of Prince, Paris and Blanket gleefully receiving their gifts, which included the puppy, Kenya.
___
Chase had been working at Jackson's home for only a few days when it came time to prepare for Paris' 11th birthday.
She wanted a Michael Jackson-themed party.
All around the dining room, posters of the King of Pop were hung alongside album covers and other pictures. Jackson's hit songs played as the family ate cheese pizza, hot wings and banana splits, Chase recalled.
Paris' birthday cake was decorated with Lilo & Stitch, her favorite Disney characters. But the festivities weren't over.
Jackson escorted the children into the backyard, where they watched a private Cirque du Soleil-style circus, complete with men on stilts and a woman performing in a giant balloon.
Chase watched from the kitchen window and later described the scene as "the most beautiful expression of love I've ever seen."
___
Jackson spent the final months of his life in a rented mansion in the upscale Holmby Hills section of Los Angeles.
The mansion had all the amenities fit for a pop superstar ? a palatial entryway, staircase and parlor and in the basement, a home theater and dance studio.
The house was a hub of activity, with security guards posted outside, a pair of housekeepers, a nanny for the children and on many days, a personal chef stationed in the kitchen.
Dinners at the home occasionally featured special guests, including Jackson's personal physician Conrad Murray and choreographer Travis Payne.
But staffers and guests other than Murray weren't allowed upstairs, where the bedrooms were. When Chase wanted to prepare a soul food menu for Jackson and his children, she wrote him a note in Magic Marker and left it at the foot of the stairs.
AEG Live's lead defense attorney has pointed to the secrecy of Jackson's upstairs lifestyle ? where the superstar was receiving nightly doses of the anesthetic propofol in his locked bedroom ? to support the company's contention it couldn't have known about Jackson's drug treatments.
___
Having a stable home for his children was a major motivation for Jackson returning to the concert stage, AEG executives say.
After his acquittal of child molestation charges in 2005, Jackson had become a nomad, spending time in various cities, including Las Vegas, often staying with friends.
"He wanted his kids to have a permanent place to live and a sense of community," AEG Live CEO Randy Phillips recalled Jackson telling him during one meeting held while the family was living in the guesthouse of a rich benefactor.
It was Halloween and the children darted in and out of the rooms, wearing masks. Later that night, they'd go with their father to a party at Elizabeth Taylor's home.
"I felt incredibly bad that this incredible star was at this point where he couldn't buy a house," Phillips said.
___
Jackson was always a magnet for photographers and fans, but he managed to sneak his children into a movie just weeks before his death.
The family and a few others went to see the animated film "Up" at the El Capitan Theatre on a touristy stretch of Hollywood Boulevard.
They came in a back door and remained in a private room while moviegoers filed into the theater. When everyone else was seated, the entourage, including his longtime makeup artist Karen Faye, director Kenny Ortega and others, hit up the concession stand.
The group watched the movie without distraction. "No one knew Michael was there," Faye recalled.
___
Jackson and choreographer Travis Payne were scheduled to rehearse one-on-one several days a week in the dance studio that was in the basement of Jackson's mansion.
It's unclear how often the pair worked out, but when they did they often had a companion, 7-year-old Blanket. He liked to watch his father dance, Payne later recalled, and tried to always stay close to his dad. During their workouts, Payne said Jackson talked to his son, mentoring him.
Preparations for the shows meant that Jackson was frequently out of the house at meetings, film shoots or rehearsals. When he returned home, Prince, Paris and Blanket would rush their father.
"They would take off like lightning," Chase recalls, "... and grab him around the ankles and around the waist."
They'd be hanging off of him, not unlike a picture shown to jurors during opening statements.
In the photo, Jackson was handing Blanket, then a newborn, to President Bill Clinton. Clinging to Jackson's right leg was Paris.
___
When it came time for a science project, Paris settled on studying snails.
She enlisted Chase to help her find snails in the mansion's backyard. The pair carried large flashlights and found several of the slimy creatures and prepared to bring them inside.
Jackson was waiting for them.
"At this point, I knew I was going to get fired," Chase recalled.
The singer looked at the snails and had a different reaction ? he helped make them a home.
The snails ended up in jars made cozier by moss in the bottom and tiny cocktail umbrellas. They lived on the kitchen counter, not far from other reminders of the children.
Blanket's colorings hung on the refrigerator.
On a chalkboard where Chase would write out menus, Paris scrawled a message that remained on the board the day her father died.
"I love daddy," the 11-year-old wrote. "Smile, it's free."
___
Anthony McCartney can be reached at http://twitter.com/mccartneyAP
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Apparently Google is internally testing a service called "Google Mine" that lets you index all your crap on Google+. Like, the physical items you own. You'll be able to share them on Google+ and set statuses for them like "given away," "gift recieved" or "had in the past." Of course Google would like to know that.
Source: http://gizmodo.com/apparently-google-is-internally-testing-a-service-calle-531459420
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SPRINGFIELD, Mo. (AP) ? A southwest Missouri woman is charged with using antifreeze to fatally poison her husband and son and attempt to kill her daughter over a 14-month period.
Fifty-one-year-old Diane Staudte of Springfield was charged Friday with two counts of first-degree murder, one count of first-degree assault and one count of armed criminal action. She is being held without bond. It isn't immediately clear if she has an attorney.
The probable cause statement says authorities received an anonymous tip earlier this month.
The statement says Staudte admitted under questioning to killing her husband, 61-year-old Mark Staudte, in April 2012 and her son, 26-year-old Shawn Staudte, in September.
The statement also says she admitted poisoning her daughter, 24-year-old Sarah Staudte, this month. She survived.
Source: http://news.yahoo.com/mo-woman-charged-antifreeze-poisoning-deaths-171144432.html
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June 20, 2013 ? A team of NUS researchers from the Departments of Bioengineering and Orthopaedic Surgery has developed a highly realistic three-dimensional (3-D) tumour model. As it replicates the conditions in the body, it is able to track the effectiveness and progress of drug therapy. Their model has the potential to be a more effective method for studying tumours than in-vitro and even in-vivo methods.
The team comprised Professor James Goh, Associate Professor Toh Siew Lok and Dr Pamela Tan from the Department of Bioengineering at NUS Faculty of Engineering, and Associate Professor Saminathan Suresh Nathan from the Department of Orthopaedic Surgery at the NUS Yong Loo Lin School of Medicine, who carried out their study using osteosarcoma, which is the most prevalent form of paediatric primary bone cancer.
Reconstructing tumours in the laboratory has been a hot topic for research as current methods of testing have not been sufficient to yield concrete results.
Dr Tan, who has been researching on the 3-D model for her PhD thesis, said: "Despite the urgent need to develop cancer therapeutics, little progress has been made due to the lack of good pre-clinical drug testing models. Current laboratory drug testing methods yield results that differ largely from animal testing because of the use of 2-D cell culture systems which cannot replicate the 3-D properties of the tumour tissue."
In in-vitro testing, cell culture systems are largely 2-D, hence, lack the structural features of the 3-D microenvironment. On the other hand, it is not feasible to carry out large-scale molecular biology research using in-vivo experiments. Furthermore, society has become increasingly concerned about the use of animals in experimentation.
Prof Goh said that tissue engineering, a major focus of study at the Department of Bioengineering, can help bridge these gaps, thereby establishing a more physiological 3-D in-vitro model. The team made use of techniques from tissue engineering to fabricate the 3-D tumour model and reconstructed the tumour tissue into factors and cell types in order to form a clinically relevant tumour.
The team decided to use silk to fabricate the scaffolds onto which the osteosarcoma cells were grown because it has been demonstrated to have excellent properties for cell attachment and growth.
Their 3-D tumour construct gives results that are much closer to those obtained from in-vivo studies, as compared to 2-D in-vitro studies. When chemotherapeutic drugs (which target aggressively growing cells) were tested on the 3-D tumour constructs, their effectiveness in killing cancer cells was greatly reduced, compared to testing the same drugs using the standard 2-D system. Moreover, the therapeutic doses found using the 3-D tumour constructs was within those measured in mice, indicating that the constructs have the potential to help bridge the gap between laboratory and animal testing, in order to improve the yield and quality of chemotherapeutic drug screening.
This is also the first time that a realistic 3-D tumour has been constructed in a laboratory using silk scaffolds in a pressurised bioreactor. Their 3-D bioreactor tumour model was able to express markers that indicate the ability of a tumour to initiate blood vessel growth at levels almost identical to that of the mouse model. The tumour constructs also responded to drugs that prevent blood vessel formation in a manner similar to that observed clinically.
"Our model also makes it possible to study how tumour cells interact with cells of the surrounding tissue, which results in more aggressive tumour behaviour," added Dr Tan.
The team has been developing the concept of the tumour microenvironment as an important determinant of tumour behaviour over the last 10 years.
Said Assoc Prof Nathan, "Dr Tan's recent contribution has shed remarkable insight into mechanisms of angiogenesis that were previously taken for granted and may now have to be re-addressed. Clinically this will have significant bearing on other drugs as well."
"We will in future be expanding our findings to other cancers and incorporating other aspects of the tumour microenvironment like oxygen levels within the system to ultimately create a platform for testing that could save much in downstream applications of experimental drugs," he added.
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ST. PETERSBURG, Russia (AP) ? Security agencies will make sure Russians fighting alongside rebels in Syria don't pose a threat to the 2014 Winter Games in Sochi, the foreign minister said Friday.
Sergey Lavrov said in an interview that the potential threat of them coming home to launch attacks "would be taken into account very seriously."
Lavrov said Moscow and Washington will cooperate on ensuring security for the Sochi Olympics, "making sure that the potentials of respective services and agencies of Russia and the United States are brought together to make the preparations more efficient."
He refused to elaborate on what specific steps will be taken.
Some observers have voiced concern that Islamic militants from Russia who have fought together with Syrian rebels could return home and try to take revenge against Russia for its support of Syrian President Bashar Assad. The chief of Russia's top security agency has said that about 200 Russians have joined the Syrian rebels, and acknowledged they could be a threat when they return.
Lavrov said nationals of European countries also have joined the rebels in Syria, and may pose a similar challenge to their home countries.
"This is not only relevant in the context of the Olympics, it's also relevant in the context of day-to-day life of entire Europe, the United States and other countries," he told The Associated Press and the Bloomberg news agency. "When this war is over ... these guys wouldn't be busy and they might look for some engagement" in the countries where they are citizens.
Russian officials have said that they have taken all necessary precautions to ensure the 2014 Winter Games in the Black Sea resort of Sochi will be "the safest Olympics in history." But security experts have pointed at an Islamic insurgency across the North Caucasus mountains that tower over Sochi, saying it could put President Vladimir Putin's pet project at risk.
The elder of the two ethnic Chechen brothers from Russia who are accused of staging the Boston Marathon bombings spent six months last year in the restive Russian province of Dagestan, which lies about 500 kilometers (300 miles) east of Sochi. Russian investigators have been trying to determine whether he had contact with local Islamic militants.
Dagestan has become the epicenter of Islamic insurgency that has destabilized the North Caucasus, with rebels mounting daily attacks on police and other officials.
Lavrov sought to downplay the threat posed by militants in the Caucasus. "Terrorist attacks happen, they aren't as numerous as before, and the Russian security services are becoming much more efficient in not only fighting the terrorists but also in preventing terrorist attacks," he said.
Source: http://news.yahoo.com/lavrov-russian-rebels-pose-no-risk-sochi-181451831.html
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