Sunday, June 23, 2013

Trial provides portrait of Jackson as a father

FILE - In this Oct. 8, 2011 file photo, from left, Prince Jackson, Prince Michael II "Blanket"Jackson and Paris Jackson arrive on stage at the Michael Forever the Tribute Concert, at the Millennium Stadium in Cardiff, Wales. Jurors hearing a civil case in Los Angeles filed by Jackson?s mother, Katherine Jackson, have heard numerous stories about the entertainer?s devotion to his children as expressed through extravagant birthday parties and secret family outings. The tender moments have been described throughout the trial, which concluded its eighth week on Friday, June 21, 2013. (AP Photo/Joel Ryan, file) *Editorial Use Only*

FILE - In this Oct. 8, 2011 file photo, from left, Prince Jackson, Prince Michael II "Blanket"Jackson and Paris Jackson arrive on stage at the Michael Forever the Tribute Concert, at the Millennium Stadium in Cardiff, Wales. Jurors hearing a civil case in Los Angeles filed by Jackson?s mother, Katherine Jackson, have heard numerous stories about the entertainer?s devotion to his children as expressed through extravagant birthday parties and secret family outings. The tender moments have been described throughout the trial, which concluded its eighth week on Friday, June 21, 2013. (AP Photo/Joel Ryan, file) *Editorial Use Only*

In this undated photo released by the LA Superior Court and presented as evidence, a 2009 message written by Paris Jackson about her father, Michael Jackson, is seen on a chalkboard that was placed in the kitchen of the singer?s rented mansion in Los Angeles. The message remained on the board on the day Jackson died in June 2009, and was described to a jury hearing a case in Los Angeles filed by Jackson?s mother by the singer?s chef, Kai Chase, during testimony on Tuesday, June 18, 2013. (AP Photo/LA Superior Court)

FILE - In this May 27, 2006 file photo, Michael Jackson smiles during a press conference of the MTV Video Music Awards Japan 2006 in Tokyo. The U.S. entertainer was awarded a Legend Award at the ceremony. Jurors hearing a civil case in Los Angeles filed by Jackson?s mother, Katherine Jackson, have heard numerous stories about the entertainer?s devotion to his children as expressed through extravagant birthday parties and secret family outings. The tender moments have been described throughout the trial, which concluded its eighth week on Friday, June 21, 2013. (AP Photo/Koji Sasahara, File)

FILE - In this Jan. 25, 2006 file photo, Michael Jackson, center, wears an abaya, the traditional Arabic women's veil and all-covering gown, and holds the hand of one of his children, also veiled, as they walk toward their car behind a shopping mall, in Manama, Bahrain. Jackson, a reclusive resident of the Gulf island country since being cleared of child molestation charges, was accompanied by his sister, Janet, unseen, and two other children on the shopping outing. Jurors hearing a civil case in Los Angeles filed by Jackson?s mother, Katherine Jackson, have heard numerous stories about the entertainer?s devotion to his children as expressed through extravagant birthday parties and secret family outings. The tender moments have been described throughout the trial, which concluded its eighth week on Friday, June 21, 2013. (AP Photo/Hasan Jamali, File)

LOS ANGELES (AP) ? Courtrooms have supplied the epilogue to Michael Jackson's life. They've provided the forum where his debts have been settled, his final days dissected and his life depicted as a cautionary tale.

In nearly four years of court proceedings, two juries have watched Jackson come to life on video screens. They've watched him spin, dance, and then disappear. They've heard his voice, seen his handwriting and viewed photos of his lifeless body.

His role as a father has been described in little more than platitudes. Until now.

The jury hearing a civil case filed by the superstar's mother ? against AEG Live LLC, the promoter of Jackson's ill-fated concerts ? are experiencing details of a world previously held under lock and key. They've heard of extravagant birthday parties, secret family outings and the leg-clinging devotion of his children.

Jackson shielded the youngsters from the public eye, home-schooling them and often hiding their faces in public.

Away from the cameras, Jackson tried to create an environment of love, attention and special moments for his children, Michael Joseph "Prince" Jackson Jr., Paris-Michael Katherine Jackson and Prince Michael "Blanket" Jackson.

The following are some of some of the stories they've told. They present a portrait of Jackson as a father that outsiders never saw.

___

The final month of Jackson's life was a busy time. There were rehearsals for "This Is It," planning meetings and film shoots for a series of mini-movies that would precede some of his greatest hits at the London shows.

Jackson brought his children to the shoot for a "Smooth Criminal" video that culminated with Jackson leaping through a window while being shot at by Humphrey Bogart.

Alif Sankey, a backup dancer on the original video who was working on the comeback concerts, sat next to Paris during the shoot. The 11-year-old wanted to share a secret and opened up her purse.

It was filled with candy, Sankey recalled.

Jackson didn't want his children to eat sweets, and Paris asked Sankey to keep it quiet.

The dancer noticed something else inside the purse ? tiny picture frames with images of her father.

"Her purse was full of candy and pictures of Daddy."

___

Despite being home-schooled, there was no shortage of companions for Jackson's children.

Chef Kai Chase recalled numerous pets in the mansion that Jackson was renting while he prepared for his "This Is It" shows.

There was the talking bird, Siberia, who whistled at pretty women.

The children also had a chocolate Labrador named Kenya, whom Chase bought a cookbook for so she could bake him treats and a birthday cake. Two cats, named Katie and Thriller, also roamed the house.

During opening statements of the civil trial, some of the jury's first exposure to life in the Jackson home came from footage shot on a Christmas morning several years ago. Jackson's ode to his children, "You Are My Life" played as jurors watched a video of a Christmas morning from years ago of Prince, Paris and Blanket gleefully receiving their gifts, which included the puppy, Kenya.

___

Chase had been working at Jackson's home for only a few days when it came time to prepare for Paris' 11th birthday.

She wanted a Michael Jackson-themed party.

All around the dining room, posters of the King of Pop were hung alongside album covers and other pictures. Jackson's hit songs played as the family ate cheese pizza, hot wings and banana splits, Chase recalled.

Paris' birthday cake was decorated with Lilo & Stitch, her favorite Disney characters. But the festivities weren't over.

Jackson escorted the children into the backyard, where they watched a private Cirque du Soleil-style circus, complete with men on stilts and a woman performing in a giant balloon.

Chase watched from the kitchen window and later described the scene as "the most beautiful expression of love I've ever seen."

___

Jackson spent the final months of his life in a rented mansion in the upscale Holmby Hills section of Los Angeles.

The mansion had all the amenities fit for a pop superstar ? a palatial entryway, staircase and parlor and in the basement, a home theater and dance studio.

The house was a hub of activity, with security guards posted outside, a pair of housekeepers, a nanny for the children and on many days, a personal chef stationed in the kitchen.

Dinners at the home occasionally featured special guests, including Jackson's personal physician Conrad Murray and choreographer Travis Payne.

But staffers and guests other than Murray weren't allowed upstairs, where the bedrooms were. When Chase wanted to prepare a soul food menu for Jackson and his children, she wrote him a note in Magic Marker and left it at the foot of the stairs.

AEG Live's lead defense attorney has pointed to the secrecy of Jackson's upstairs lifestyle ? where the superstar was receiving nightly doses of the anesthetic propofol in his locked bedroom ? to support the company's contention it couldn't have known about Jackson's drug treatments.

___

Having a stable home for his children was a major motivation for Jackson returning to the concert stage, AEG executives say.

After his acquittal of child molestation charges in 2005, Jackson had become a nomad, spending time in various cities, including Las Vegas, often staying with friends.

"He wanted his kids to have a permanent place to live and a sense of community," AEG Live CEO Randy Phillips recalled Jackson telling him during one meeting held while the family was living in the guesthouse of a rich benefactor.

It was Halloween and the children darted in and out of the rooms, wearing masks. Later that night, they'd go with their father to a party at Elizabeth Taylor's home.

"I felt incredibly bad that this incredible star was at this point where he couldn't buy a house," Phillips said.

___

Jackson was always a magnet for photographers and fans, but he managed to sneak his children into a movie just weeks before his death.

The family and a few others went to see the animated film "Up" at the El Capitan Theatre on a touristy stretch of Hollywood Boulevard.

They came in a back door and remained in a private room while moviegoers filed into the theater. When everyone else was seated, the entourage, including his longtime makeup artist Karen Faye, director Kenny Ortega and others, hit up the concession stand.

The group watched the movie without distraction. "No one knew Michael was there," Faye recalled.

___

Jackson and choreographer Travis Payne were scheduled to rehearse one-on-one several days a week in the dance studio that was in the basement of Jackson's mansion.

It's unclear how often the pair worked out, but when they did they often had a companion, 7-year-old Blanket. He liked to watch his father dance, Payne later recalled, and tried to always stay close to his dad. During their workouts, Payne said Jackson talked to his son, mentoring him.

Preparations for the shows meant that Jackson was frequently out of the house at meetings, film shoots or rehearsals. When he returned home, Prince, Paris and Blanket would rush their father.

"They would take off like lightning," Chase recalls, "... and grab him around the ankles and around the waist."

They'd be hanging off of him, not unlike a picture shown to jurors during opening statements.

In the photo, Jackson was handing Blanket, then a newborn, to President Bill Clinton. Clinging to Jackson's right leg was Paris.

___

When it came time for a science project, Paris settled on studying snails.

She enlisted Chase to help her find snails in the mansion's backyard. The pair carried large flashlights and found several of the slimy creatures and prepared to bring them inside.

Jackson was waiting for them.

"At this point, I knew I was going to get fired," Chase recalled.

The singer looked at the snails and had a different reaction ? he helped make them a home.

The snails ended up in jars made cozier by moss in the bottom and tiny cocktail umbrellas. They lived on the kitchen counter, not far from other reminders of the children.

Blanket's colorings hung on the refrigerator.

On a chalkboard where Chase would write out menus, Paris scrawled a message that remained on the board the day her father died.

"I love daddy," the 11-year-old wrote. "Smile, it's free."

___

Anthony McCartney can be reached at http://twitter.com/mccartneyAP

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-06-22-Michael%20Jackson-Fatherhood/id-f38529cb916246fba97f8237efefdc90

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Stock Markets News Headlines - Yahoo! News

Stock Markets News Headlines - Yahoo! Newshttp://news.yahoo.com/stocks/ Get the latest stock markets news headlines from Yahoo! News. Find breaking stock markets news, including analysis and opinion on top stock markets stories, photos and more.en-USCopyright (c) 2013 Yahoo! Inc. All rights reservedFri, 21 Jun 2013 21:37:31 -04005Stock Markets News Headlines - Yahoo! 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(AP Photo/Richard Drew)" align="left" title="Specialist Joseph Mastrolia, left, and trader George Ettinger work on the floor of the New York Stock Exchange, Friday, June 21, 2013. U.S. stocks rose in morning trading on Friday as traders regrouped following the biggest drop of the year. (AP Photo/Richard Drew)" border="0" /></a>Stocks edged lower on Friday, but nothing like the plunge they took earlier this week.</p><br clear="all"/>http://news.yahoo.com/stocks-mostly-lower-wall-street-170004639.htmlFri, 21 Jun 2013 13:00:04 -0400Associated Pressstocks-mostly-lower-wall-street-170004639<p><a href="http://news.yahoo.com/stocks-mostly-lower-wall-street-170004639.html"><img src="http://l.yimg.com/bt/api/res/1.2/21oOETEAdguL80tr3Ew4Sg--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/ap_webfeeds/2b4661fbc5de6714350f6a70670057b0.jpg" width="130" height="86" alt="Specialist Joseph Mastrolia, left, and trader George Ettinger work on the floor of the New York Stock Exchange, Friday, June 21, 2013. U.S. stocks rose in morning trading on Friday as traders regrouped following the biggest drop of the year. (AP Photo/Richard Drew)" align="left" title="Specialist Joseph Mastrolia, left, and trader George Ettinger work on the floor of the New York Stock Exchange, Friday, June 21, 2013. U.S. stocks rose in morning trading on Friday as traders regrouped following the biggest drop of the year. (AP Photo/Richard Drew)" border="0" /></a>Stocks edged lower on Friday, but nothing like the plunge they took earlier this week.</p><br clear="all"/>US stocks edge lower after a two-day plunge<p><a href="http://news.yahoo.com/us-stocks-edge-lower-two-day-plunge-155222257.html"><img src="http://l1.yimg.com/bt/api/res/1.2/QV9Lg1o5CIqmWJtCPFo70A--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/ap_webfeeds/819fa19bc5dd6714350f6a70670071c3.jpg" width="130" height="86" alt="Specialist Gregg Maloney, left, works with a trader on the floor of the New York Stock Exchange, Friday, June 21, 2013. U.S. stocks rose in morning trading on Friday as traders regrouped following the biggest drop of the year. (AP Photo/Richard Drew)" align="left" title="Specialist Gregg Maloney, left, works with a trader on the floor of the New York Stock Exchange, Friday, June 21, 2013. U.S. stocks rose in morning trading on Friday as traders regrouped following the biggest drop of the year. (AP Photo/Richard Drew)" border="0" /></a>The stock market is edging lower in midday trading as investors regroup following the biggest drop of the year.</p><br clear="all"/>http://news.yahoo.com/us-stocks-edge-lower-two-day-plunge-155222257.htmlFri, 21 Jun 2013 11:52:22 -0400Associated Pressus-stocks-edge-lower-two-day-plunge-155222257<p><a href="http://news.yahoo.com/us-stocks-edge-lower-two-day-plunge-155222257.html"><img src="http://l1.yimg.com/bt/api/res/1.2/QV9Lg1o5CIqmWJtCPFo70A--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/ap_webfeeds/819fa19bc5dd6714350f6a70670071c3.jpg" width="130" height="86" alt="Specialist Gregg Maloney, left, works with a trader on the floor of the New York Stock Exchange, Friday, June 21, 2013. U.S. stocks rose in morning trading on Friday as traders regrouped following the biggest drop of the year. (AP Photo/Richard Drew)" align="left" title="Specialist Gregg Maloney, left, works with a trader on the floor of the New York Stock Exchange, Friday, June 21, 2013. U.S. stocks rose in morning trading on Friday as traders regrouped following the biggest drop of the year. (AP Photo/Richard Drew)" border="0" /></a>The stock market is edging lower in midday trading as investors regroup following the biggest drop of the year.</p><br clear="all"/>US stocks calmer after 2-day plunge<p><a href="http://news.yahoo.com/us-stocks-calmer-2-day-plunge-153452122.html"><img src="http://l2.yimg.com/bt/api/res/1.2/LPc8Jj9B76frVXKCYYNf.Q--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/ap_webfeeds/56101da7c4c76114350f6a7067004fdd.jpg" width="130" height="86" alt="In this Thursday, June 20, 2013, photo, specialist John Parisi, right, works with traders on the floor of the New York Stock Exchange.Asian stocks endured moderate losses Friday June 21, 2013 but European markets appeared set to stabilize even though investors remained edgy about a possible change of course by the U.S. Federal Reserve. (AP Photo/Richard Drew)" align="left" title="In this Thursday, June 20, 2013, photo, specialist John Parisi, right, works with traders on the floor of the New York Stock Exchange.Asian stocks endured moderate losses Friday June 21, 2013 but European markets appeared set to stabilize even though investors remained edgy about a possible change of course by the U.S. Federal Reserve. (AP Photo/Richard Drew)" border="0" /></a>Wall Street steadied after a two-day plunge caused by news that the Federal Reserve was getting ready to wind down its massive bond-buying program by mid-2014.</p><br clear="all"/>http://news.yahoo.com/us-stocks-calmer-2-day-plunge-153452122.htmlFri, 21 Jun 2013 11:34:52 -0400Associated Pressus-stocks-calmer-2-day-plunge-153452122<p><a href="http://news.yahoo.com/us-stocks-calmer-2-day-plunge-153452122.html"><img src="http://l2.yimg.com/bt/api/res/1.2/LPc8Jj9B76frVXKCYYNf.Q--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/ap_webfeeds/56101da7c4c76114350f6a7067004fdd.jpg" width="130" height="86" alt="In this Thursday, June 20, 2013, photo, specialist John Parisi, right, works with traders on the floor of the New York Stock Exchange.Asian stocks endured moderate losses Friday June 21, 2013 but European markets appeared set to stabilize even though investors remained edgy about a possible change of course by the U.S. Federal Reserve. (AP Photo/Richard Drew)" align="left" title="In this Thursday, June 20, 2013, photo, specialist John Parisi, right, works with traders on the floor of the New York Stock Exchange.Asian stocks endured moderate losses Friday June 21, 2013 but European markets appeared set to stabilize even though investors remained edgy about a possible change of course by the U.S. Federal Reserve. (AP Photo/Richard Drew)" border="0" /></a>Wall Street steadied after a two-day plunge caused by news that the Federal Reserve was getting ready to wind down its massive bond-buying program by mid-2014.</p><br clear="all"/>London new share listings revival driven by rising markets<p><a href="http://news.yahoo.com/london-share-listings-revival-driven-rising-markets-142322288.html"><img src="http://l2.yimg.com/bt/api/res/1.2/S73CpYu0NMBj15td4KbqFQ--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-21T142322Z_1_CBRE95K13Z100_RTROPTP_2_MARKETS-BRITAIN-STOCKS.JPG" width="130" height="86" alt="A trader works on the trading floor in London" align="left" title="A trader works on the trading floor in London" border="0" /></a>By Kylie MacLellan LONDON (Reuters) - Rising share prices, rather than different procedures, have helped to spur a revival in new listings in London this year and some bankers and investors believe more could be done to improve the process of bringing a company to market. The amount raised from new share listings on London&#039;s main stock market this year is more than four times that in the same period in 2012, according to London Stock Exchange data. British companies alone have raised more than 1.5 billion pounds. ...</p><br clear="all"/>http://news.yahoo.com/london-share-listings-revival-driven-rising-markets-142322288.htmlFri, 21 Jun 2013 10:23:22 -0400Reuterslondon-share-listings-revival-driven-rising-markets-142322288<p><a href="http://news.yahoo.com/london-share-listings-revival-driven-rising-markets-142322288.html"><img src="http://l2.yimg.com/bt/api/res/1.2/S73CpYu0NMBj15td4KbqFQ--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-21T142322Z_1_CBRE95K13Z100_RTROPTP_2_MARKETS-BRITAIN-STOCKS.JPG" width="130" height="86" alt="A trader works on the trading floor in London" align="left" title="A trader works on the trading floor in London" border="0" /></a>By Kylie MacLellan LONDON (Reuters) - Rising share prices, rather than different procedures, have helped to spur a revival in new listings in London this year and some bankers and investors believe more could be done to improve the process of bringing a company to market. The amount raised from new share listings on London&#039;s main stock market this year is more than four times that in the same period in 2012, according to London Stock Exchange data. British companies alone have raised more than 1.5 billion pounds. ...</p><br clear="all"/>Wall Street gains modestly after two-day selloff<p><a href="http://news.yahoo.com/wall-street-gains-modestly-two-day-selloff-135311727.html"><img src="http://l2.yimg.com/bt/api/res/1.2/qEw._xar5AYCjkAlaUSR_Q--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-21T135311Z_1_CDEE95K12KP00_RTROPTP_2_MARKETS-USA-STOCKS.JPG" width="130" height="86" alt="Traders work on the floor at the New York Stock Exchange, June 20, 2013. REUTERS/Brendan McDermid" align="left" title="Traders work on the floor at the New York Stock Exchange, June 20, 2013. REUTERS/Brendan McDermid" border="0" /></a>By Rodrigo Campos NEW YORK (Reuters) - U.S. stocks edged higher at the open on Friday, bouncing back from a two-day selloff triggered by concern over the future of central bank stimulus, but major indexes were still on track to post sharp losses for the week. A sharp drop in Oracle shares offset kept the Nasdaq Composite little changed. Share prices had slumped since Wednesday, when Federal Reserve Chairman Ben Bernanke laid out the Fed&#039;s plans to pull back on its $85 billion in monthly asset purchases. ...</p><br clear="all"/>http://news.yahoo.com/wall-street-gains-modestly-two-day-selloff-135311727.htmlFri, 21 Jun 2013 09:53:11 -0400Reuterswall-street-gains-modestly-two-day-selloff-135311727<p><a href="http://news.yahoo.com/wall-street-gains-modestly-two-day-selloff-135311727.html"><img src="http://l2.yimg.com/bt/api/res/1.2/qEw._xar5AYCjkAlaUSR_Q--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-21T135311Z_1_CDEE95K12KP00_RTROPTP_2_MARKETS-USA-STOCKS.JPG" width="130" height="86" alt="Traders work on the floor at the New York Stock Exchange, June 20, 2013. REUTERS/Brendan McDermid" align="left" title="Traders work on the floor at the New York Stock Exchange, June 20, 2013. REUTERS/Brendan McDermid" border="0" /></a>By Rodrigo Campos NEW YORK (Reuters) - U.S. stocks edged higher at the open on Friday, bouncing back from a two-day selloff triggered by concern over the future of central bank stimulus, but major indexes were still on track to post sharp losses for the week. A sharp drop in Oracle shares offset kept the Nasdaq Composite little changed. Share prices had slumped since Wednesday, when Federal Reserve Chairman Ben Bernanke laid out the Fed&#039;s plans to pull back on its $85 billion in monthly asset purchases. ...</p><br clear="all"/>US stocks open higher after a two-day plunge<p><a href="http://news.yahoo.com/us-stocks-open-higher-two-day-plunge-134401163.html"><img src="http://l2.yimg.com/bt/api/res/1.2/LPc8Jj9B76frVXKCYYNf.Q--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/ap_webfeeds/56101da7c4c76114350f6a7067004fdd.jpg" width="130" height="86" alt="In this Thursday, June 20, 2013, photo, specialist John Parisi, right, works with traders on the floor of the New York Stock Exchange.Asian stocks endured moderate losses Friday June 21, 2013 but European markets appeared set to stabilize even though investors remained edgy about a possible change of course by the U.S. Federal Reserve. (AP Photo/Richard Drew)" align="left" title="In this Thursday, June 20, 2013, photo, specialist John Parisi, right, works with traders on the floor of the New York Stock Exchange.Asian stocks endured moderate losses Friday June 21, 2013 but European markets appeared set to stabilize even though investors remained edgy about a possible change of course by the U.S. Federal Reserve. (AP Photo/Richard Drew)" border="0" /></a>The U.S. stock market is opening higher as traders regroup following the biggest drop of the year.</p><br clear="all"/>http://news.yahoo.com/us-stocks-open-higher-two-day-plunge-134401163.htmlFri, 21 Jun 2013 09:44:01 -0400Associated Pressus-stocks-open-higher-two-day-plunge-134401163<p><a href="http://news.yahoo.com/us-stocks-open-higher-two-day-plunge-134401163.html"><img src="http://l2.yimg.com/bt/api/res/1.2/LPc8Jj9B76frVXKCYYNf.Q--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/ap_webfeeds/56101da7c4c76114350f6a7067004fdd.jpg" width="130" height="86" alt="In this Thursday, June 20, 2013, photo, specialist John Parisi, right, works with traders on the floor of the New York Stock Exchange.Asian stocks endured moderate losses Friday June 21, 2013 but European markets appeared set to stabilize even though investors remained edgy about a possible change of course by the U.S. Federal Reserve. (AP Photo/Richard Drew)" align="left" title="In this Thursday, June 20, 2013, photo, specialist John Parisi, right, works with traders on the floor of the New York Stock Exchange.Asian stocks endured moderate losses Friday June 21, 2013 but European markets appeared set to stabilize even though investors remained edgy about a possible change of course by the U.S. Federal Reserve. (AP Photo/Richard Drew)" border="0" /></a>The U.S. stock market is opening higher as traders regroup following the biggest drop of the year.</p><br clear="all"/>Wall Street Fundamentals Releases New In-Depth Stock Reports on FCX, SCCO, TCK and TGBDisappointing manufacturing data from China and news that the Federal Reserve would begin to scale back stimulus measures have combined to send copper futures sliding to a seven-week low. On Thursday, ...http://news.yahoo.com/wall-street-fundamentals-releases-depth-stock-reports-fcx-120000931.htmlFri, 21 Jun 2013 08:00:00 -0400Accesswirewall-street-fundamentals-releases-depth-stock-reports-fcx-120000931Wall Street Fundamentals Releases New In-Depth Stock Reports on CLX, GE, KO and MMMThe market posted its largest declined in 2013 Thursday after the Federal Reserve announced plans to begin curbing stimulus measures. The Dow Jones Industrial Average declined 2.3 percent to close at 14758.32, ...http://news.yahoo.com/wall-street-fundamentals-releases-depth-stock-reports-clx-120000472.htmlFri, 21 Jun 2013 08:00:00 -0400Accesswirewall-street-fundamentals-releases-depth-stock-reports-clx-120000472Wall Street Fundamentals Releases New In-Depth Stock Reports on BHI, KMI, RRC and WPXEnergy stocks in the S&P 500 Index fell across the board Thursday after the Federal Reserve announced plans to begin curbing stimulus measures. The SPDR Energy Select Sector ETF (NYSEARCA: XLE) declined ...http://news.yahoo.com/wall-street-fundamentals-releases-depth-stock-reports-bhi-120000546.htmlFri, 21 Jun 2013 08:00:00 -0400Accesswirewall-street-fundamentals-releases-depth-stock-reports-bhi-120000546Wall Street Fundamentals Releases New In-Depth Stock Reports on ESV, HP, NBR and SLBEnergy stocks in the S&P 500 Index fell across the board Thursday after the Federal Reserve announced plans to begin curbing stimulus measures. The SPDR Energy Select Sector ETF (NYSEARCA: XLE) declined ...http://news.yahoo.com/wall-street-fundamentals-releases-depth-stock-reports-esv-120000531.htmlFri, 21 Jun 2013 08:00:00 -0400Accesswirewall-street-fundamentals-releases-depth-stock-reports-esv-120000531Olive Garden parent Darden quarterly sales beat Wall Street<p><a href="http://news.yahoo.com/olive-garden-parent-darden-quarterly-sales-beat-wall-111811233.html"><img src="http://l3.yimg.com/bt/api/res/1.2/39JVn3sYkKhyGiFn6xKTEw--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-21T111811Z_1_CBRE95K0VEF00_RTROPTP_2_USA.JPG" width="130" height="86" alt="A man talks on his mobile phone in front of the Times Square Olive Garden in New York" align="left" title="A man talks on his mobile phone in front of the Times Square Olive Garden in New York" border="0" /></a>(Reuters) - Darden Restaurants Inc reported better-than-expected quarterly sales, helped by aggressive promotions and an expanded menu at its Olive Garden and Red Lobster chains. Sales rose 11 percent to $2.29 billion in the fourth quarter, topping analysts&#039; expectation of $2.27 billion. Overall same-restaurant sales rose 2.2 percent. Net income for the ended May 26, fell to $133.2 million, or $1.01 per share, from $151.2 million, or $1.15 per share, a year earlier. Analysts on average expected the company to earn $1.03 per share, according to Thomson Reuters I/B/E/S. ...</p><br clear="all"/>http://news.yahoo.com/olive-garden-parent-darden-quarterly-sales-beat-wall-111811233.htmlFri, 21 Jun 2013 07:18:11 -0400Reutersolive-garden-parent-darden-quarterly-sales-beat-wall-111811233<p><a href="http://news.yahoo.com/olive-garden-parent-darden-quarterly-sales-beat-wall-111811233.html"><img src="http://l3.yimg.com/bt/api/res/1.2/39JVn3sYkKhyGiFn6xKTEw--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-21T111811Z_1_CBRE95K0VEF00_RTROPTP_2_USA.JPG" width="130" height="86" alt="A man talks on his mobile phone in front of the Times Square Olive Garden in New York" align="left" title="A man talks on his mobile phone in front of the Times Square Olive Garden in New York" border="0" /></a>(Reuters) - Darden Restaurants Inc reported better-than-expected quarterly sales, helped by aggressive promotions and an expanded menu at its Olive Garden and Red Lobster chains. Sales rose 11 percent to $2.29 billion in the fourth quarter, topping analysts&#039; expectation of $2.27 billion. Overall same-restaurant sales rose 2.2 percent. Net income for the ended May 26, fell to $133.2 million, or $1.01 per share, from $151.2 million, or $1.15 per share, a year earlier. Analysts on average expected the company to earn $1.03 per share, according to Thomson Reuters I/B/E/S. ...</p><br clear="all"/>TSX loses 300 points as world markets sell offThe Toronto stock market fell sharply as traders digested disappointing Chinese manufacturing data and word Wednesday that the U.S. Federal Reserve is planning to wind down some stimulus spending.http://news.yahoo.com/tsx-loses-300-points-world-markets-sell-off-023247520.htmlThu, 20 Jun 2013 22:32:47 -0400CBCtsx-loses-300-points-world-markets-sell-off-023247520Anxiety grows as stock market learns to walk on its own<p><a href="http://news.yahoo.com/anxiety-grows-stock-market-learns-walk-own-000731034.html"><img src="http://l2.yimg.com/bt/api/res/1.2/0ECckvBRlnNxK9QqHxlorA--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-21T000731Z_1_CDEE95K00CO00_RTROPTP_2_ANALYSIS-GLOBAL-STOCK-MARKET.JPG" width="130" height="86" alt="(Blank Headline Received)" align="left" title="(Blank Headline Received)" border="0" /></a>By Rodrigo Campos NEW YORK (Reuters) - The stock market has been put on notice by the Federal Reserve: from here on in, you&#039;re on your own. Stock markets worldwide have fallen sharply since comments on Wednesday by Fed Chairman Ben Bernanke laying out the U.S. central bank&#039;s plans to pull back on its $85 billion in monthly asset purchases. U.S. stocks endured their worst two-day selloff since November 2011, and the Dow Jones industrials fell 354 points on Thursday. ...</p><br clear="all"/>http://news.yahoo.com/anxiety-grows-stock-market-learns-walk-own-000731034.htmlThu, 20 Jun 2013 20:07:31 -0400Reutersanxiety-grows-stock-market-learns-walk-own-000731034<p><a href="http://news.yahoo.com/anxiety-grows-stock-market-learns-walk-own-000731034.html"><img src="http://l2.yimg.com/bt/api/res/1.2/0ECckvBRlnNxK9QqHxlorA--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-21T000731Z_1_CDEE95K00CO00_RTROPTP_2_ANALYSIS-GLOBAL-STOCK-MARKET.JPG" width="130" height="86" alt="(Blank Headline Received)" align="left" title="(Blank Headline Received)" border="0" /></a>By Rodrigo Campos NEW YORK (Reuters) - The stock market has been put on notice by the Federal Reserve: from here on in, you&#039;re on your own. Stock markets worldwide have fallen sharply since comments on Wednesday by Fed Chairman Ben Bernanke laying out the U.S. central bank&#039;s plans to pull back on its $85 billion in monthly asset purchases. U.S. stocks endured their worst two-day selloff since November 2011, and the Dow Jones industrials fell 354 points on Thursday. ...</p><br clear="all"/>Wall St. plunges, S&P posts biggest drop since Nov 2011<p><a href="http://news.yahoo.com/stock-futures-drop-wake-feds-stimulus-tapering-outline-114830321.html"><img src="http://l.yimg.com/bt/api/res/1.2/xLGKo5DuX0IvfHAUQOnDcg--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-20T233826Z_1_CBRE95J1LQ600_RTROPTP_2_MARKETS-STOCKS.JPG" width="130" height="86" alt="Traders work on the floor at the New York Stock Exchange" align="left" title="Traders work on the floor at the New York Stock Exchange" border="0" /></a>By Ryan Vlastelica NEW YORK (Reuters) - Stocks fell more than 2 percent on Thursday, extending the previous day&#039;s sharp decline as investors fretted over the Federal Reserve&#039;s plan to begin reducing its stimulus later this year if the economy strengthens. The S&amp;P 500 recorded its biggest daily decline since November 11, 2011, on the year&#039;s heaviest day of trading. All 10 S&amp;P sectors were sharply lower, with 94 percent of stocks traded on the New York Stock Exchange down for the day and more than four-fifths of Nasdaq-listed shares ending lower. The Dow Jones industrial average dived 353. ...</p><br clear="all"/>http://news.yahoo.com/stock-futures-drop-wake-feds-stimulus-tapering-outline-114830321.htmlThu, 20 Jun 2013 19:38:26 -0400Reutersstock-futures-drop-wake-feds-stimulus-tapering-outline-114830321<p><a href="http://news.yahoo.com/stock-futures-drop-wake-feds-stimulus-tapering-outline-114830321.html"><img src="http://l.yimg.com/bt/api/res/1.2/xLGKo5DuX0IvfHAUQOnDcg--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-20T233826Z_1_CBRE95J1LQ600_RTROPTP_2_MARKETS-STOCKS.JPG" width="130" height="86" alt="Traders work on the floor at the New York Stock Exchange" align="left" title="Traders work on the floor at the New York Stock Exchange" border="0" /></a>By Ryan Vlastelica NEW YORK (Reuters) - Stocks fell more than 2 percent on Thursday, extending the previous day&#039;s sharp decline as investors fretted over the Federal Reserve&#039;s plan to begin reducing its stimulus later this year if the economy strengthens. The S&amp;P 500 recorded its biggest daily decline since November 11, 2011, on the year&#039;s heaviest day of trading. All 10 S&amp;P sectors were sharply lower, with 94 percent of stocks traded on the New York Stock Exchange down for the day and more than four-fifths of Nasdaq-listed shares ending lower. The Dow Jones industrial average dived 353. ...</p><br clear="all"/>Oracle's fiscal 4Q sales disappoint Wall St. againSAN FRANCISCO (AP) ? Oracle is still having trouble closing enough business software deals to keep Wall Street happy.http://news.yahoo.com/oracles-fiscal-4q-sales-disappoint-wall-st-again-202337131.htmlThu, 20 Jun 2013 18:13:02 -0400Associated Pressoracles-fiscal-4q-sales-disappoint-wall-st-again-202337131Analysis: Anxiety grows as stock market learns to walk on its own<p><a href="http://news.yahoo.com/analysis-anxiety-grows-stock-market-learns-walk-own-215020349.html"><img src="http://l2.yimg.com/bt/api/res/1.2/5ilyG4CKdn9KotrmD.EzsA--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-20T215020Z_1_CBRE95J1OO300_RTROPTP_2_CBUSINESS-US-USA-FED-STOCKS.JPG" width="130" height="86" alt="Traders work on floor at the New York Stock Exchange" align="left" title="Traders work on floor at the New York Stock Exchange" border="0" /></a>By Rodrigo Campos NEW YORK (Reuters) - The stock market has been put on notice by the Federal Reserve: from here on in, you&#039;re on your own. Stock markets worldwide have fallen sharply since comments on Wednesday by Fed Chairman Ben Bernanke laying out the U.S. central bank&#039;s plans to pull back on its $85 billion in monthly asset purchases. U.S. stocks endured their worst two-day selloff since November 2011, and the Dow Jones industrials fell 354 points on Thursday. ...</p><br clear="all"/>http://news.yahoo.com/analysis-anxiety-grows-stock-market-learns-walk-own-215020349.htmlThu, 20 Jun 2013 17:50:20 -0400Reutersanalysis-anxiety-grows-stock-market-learns-walk-own-215020349<p><a href="http://news.yahoo.com/analysis-anxiety-grows-stock-market-learns-walk-own-215020349.html"><img src="http://l2.yimg.com/bt/api/res/1.2/5ilyG4CKdn9KotrmD.EzsA--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-20T215020Z_1_CBRE95J1OO300_RTROPTP_2_CBUSINESS-US-USA-FED-STOCKS.JPG" width="130" height="86" alt="Traders work on floor at the New York Stock Exchange" align="left" title="Traders work on floor at the New York Stock Exchange" border="0" /></a>By Rodrigo Campos NEW YORK (Reuters) - The stock market has been put on notice by the Federal Reserve: from here on in, you&#039;re on your own. Stock markets worldwide have fallen sharply since comments on Wednesday by Fed Chairman Ben Bernanke laying out the U.S. central bank&#039;s plans to pull back on its $85 billion in monthly asset purchases. U.S. stocks endured their worst two-day selloff since November 2011, and the Dow Jones industrials fell 354 points on Thursday. ...</p><br clear="all"/>Kodak strikes post-bankruptcy loan deal with banks<p><a href="http://news.yahoo.com/kodak-strikes-post-bankruptcy-loan-deal-banks-143610685.html"><img src="http://l3.yimg.com/bt/api/res/1.2/S0aatueXjFxWp8h97LCJqA--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-20T143610Z_1_CDEE95J14KC00_RTROPTP_2_KODAK-BANKRUPTCY-LOANS.JPG" width="130" height="86" alt="DVD&#039;s by Eastman Kodak Co are displayed in a retail store in San Diego, California, April 22, 2013. REUTERS/Mike Blake" align="left" title="DVD&#039;s by Eastman Kodak Co are displayed in a retail store in San Diego, California, April 22, 2013. REUTERS/Mike Blake" border="0" /></a>REUTERS - Eastman Kodak Co said on Thursday that it had reached a $895 million financing deal with three Wall Street banks that will help fund its rebirth as commercial imaging business after the former film pioneer emerges from bankruptcy. Affiliates of JPMorgan Chase &amp; Co , Bank of America Corp and Barclays Plc will be joint lead arrangers for a senior secured term loan package of $695 million. The three banks will also arrange an asset-based revolving credit facility of $200 million. ...</p><br clear="all"/>http://news.yahoo.com/kodak-strikes-post-bankruptcy-loan-deal-banks-143610685.htmlThu, 20 Jun 2013 10:36:10 -0400Reuterskodak-strikes-post-bankruptcy-loan-deal-banks-143610685<p><a href="http://news.yahoo.com/kodak-strikes-post-bankruptcy-loan-deal-banks-143610685.html"><img src="http://l3.yimg.com/bt/api/res/1.2/S0aatueXjFxWp8h97LCJqA--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-20T143610Z_1_CDEE95J14KC00_RTROPTP_2_KODAK-BANKRUPTCY-LOANS.JPG" width="130" height="86" alt="DVD&#039;s by Eastman Kodak Co are displayed in a retail store in San Diego, California, April 22, 2013. REUTERS/Mike Blake" align="left" title="DVD&#039;s by Eastman Kodak Co are displayed in a retail store in San Diego, California, April 22, 2013. REUTERS/Mike Blake" border="0" /></a>REUTERS - Eastman Kodak Co said on Thursday that it had reached a $895 million financing deal with three Wall Street banks that will help fund its rebirth as commercial imaging business after the former film pioneer emerges from bankruptcy. Affiliates of JPMorgan Chase &amp; Co , Bank of America Corp and Barclays Plc will be joint lead arrangers for a senior secured term loan package of $695 million. The three banks will also arrange an asset-based revolving credit facility of $200 million. ...</p><br clear="all"/>Hedge fund Grandmaster sees stock market crash in China<p><a href="http://news.yahoo.com/hedge-fund-grandmaster-sees-stock-market-crash-china-135410933.html"><img src="http://l.yimg.com/bt/api/res/1.2/Ol99Wltqu7C3DpTTkufNKw--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-20T135410Z_1_CBRE95J12MD00_RTROPTP_2_MARKETS-CHINA-STOCKS-CLOSE.JPG" width="130" height="86" alt="An investor reacts in front of an electronic board showing stock information at a brokerage house in Taiyuan" align="left" title="An investor reacts in front of an electronic board showing stock information at a brokerage house in Taiyuan" border="0" /></a>By Laurence Fletcher MONTE CARLO, Monaco (Reuters) - Former chess grandmaster-turned hedge fund manager Patrick Wolff is betting on a stock market crash in China, where he says corruption and bad debts have spiralled to dangerous levels. Speaking to Reuters on the sidelines of the GAIM conference in Monaco this week, Wolff said investors were too focused on trying to work out when easy money policies will taper off in the United States and ignoring a looming correction in China. &quot;People are talking way too much about the Federal Reserve and not enough about China,&quot; he said. ...</p><br clear="all"/>http://news.yahoo.com/hedge-fund-grandmaster-sees-stock-market-crash-china-135410933.htmlThu, 20 Jun 2013 09:54:10 -0400Reutershedge-fund-grandmaster-sees-stock-market-crash-china-135410933<p><a href="http://news.yahoo.com/hedge-fund-grandmaster-sees-stock-market-crash-china-135410933.html"><img src="http://l.yimg.com/bt/api/res/1.2/Ol99Wltqu7C3DpTTkufNKw--/YXBwaWQ9eW5ld3M7Zmk9ZmlsbDtoPTg2O3E9ODU7dz0xMzA-/http://media.zenfs.com/en_us/News/Reuters/2013-06-20T135410Z_1_CBRE95J12MD00_RTROPTP_2_MARKETS-CHINA-STOCKS-CLOSE.JPG" width="130" height="86" alt="An investor reacts in front of an electronic board showing stock information at a brokerage house in Taiyuan" align="left" title="An investor reacts in front of an electronic board showing stock information at a brokerage house in Taiyuan" border="0" /></a>By Laurence Fletcher MONTE CARLO, Monaco (Reuters) - Former chess grandmaster-turned hedge fund manager Patrick Wolff is betting on a stock market crash in China, where he says corruption and bad debts have spiralled to dangerous levels. Speaking to Reuters on the sidelines of the GAIM conference in Monaco this week, Wolff said investors were too focused on trying to work out when easy money policies will taper off in the United States and ignoring a looming correction in China. &quot;People are talking way too much about the Federal Reserve and not enough about China,&quot; he said. ...</p><br clear="all"/>Kroger raises outlook on stronger 1Q profitNEW YORK (AP) ? Kroger has raised its outlook for the year after the country's largest traditional supermarket chain reported a stronger fiscal first-quarter profit that beat Wall Street expectations.http://news.yahoo.com/kroger-raises-outlook-stronger-1q-profit-130624700.htmlThu, 20 Jun 2013 09:30:01 -0400Associated Presskroger-raises-outlook-stronger-1q-profit-130624700

Source: http://rss.news.yahoo.com/rss/stocks

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Brooke Anderson Expecting Second Child

The Entertainment Tonight correspondent and her husband Jim Walker are expecting their second child in late November, Anderson announced Friday on her website.

Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/rF23HnvpwME/

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Saturday, June 22, 2013

The perfect Oxford shirt for tech users

This Summer Oxford shirt from VoyVoy is perfect for the gadget user. ?While it looks like a typical Oxford, this shirt has a couple of extra features. ?When you use the tail of ?this shirt for cleaning your glasses or touch screens, you’ll have a microfiber cleaning patch to make cleaning easier and possible less [...]

Source: http://the-gadgeteer.com/2013/06/21/the-perfect-oxford-shirt-for-tech-users/

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Apparently Google is internally testing a service called "Google Mine" that lets you index all your

Apparently Google is internally testing a service called "Google Mine" that lets you index all your crap on Google+. Like, the physical items you own. You'll be able to share them on Google+ and set statuses for them like "given away," "gift recieved" or "had in the past." Of course Google would like to know that.

Source: http://gizmodo.com/apparently-google-is-internally-testing-a-service-calle-531459420

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Mo. woman charged in antifreeze poisoning deaths

SPRINGFIELD, Mo. (AP) ? A southwest Missouri woman is charged with using antifreeze to fatally poison her husband and son and attempt to kill her daughter over a 14-month period.

Fifty-one-year-old Diane Staudte of Springfield was charged Friday with two counts of first-degree murder, one count of first-degree assault and one count of armed criminal action. She is being held without bond. It isn't immediately clear if she has an attorney.

The probable cause statement says authorities received an anonymous tip earlier this month.

The statement says Staudte admitted under questioning to killing her husband, 61-year-old Mark Staudte, in April 2012 and her son, 26-year-old Shawn Staudte, in September.

The statement also says she admitted poisoning her daughter, 24-year-old Sarah Staudte, this month. She survived.

Source: http://news.yahoo.com/mo-woman-charged-antifreeze-poisoning-deaths-171144432.html

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Friday, June 21, 2013

Realistic 3-d tumor created through tissue engineering using silk scaffolds

June 20, 2013 ? A team of NUS researchers from the Departments of Bioengineering and Orthopaedic Surgery has developed a highly realistic three-dimensional (3-D) tumour model. As it replicates the conditions in the body, it is able to track the effectiveness and progress of drug therapy. Their model has the potential to be a more effective method for studying tumours than in-vitro and even in-vivo methods.

The team comprised Professor James Goh, Associate Professor Toh Siew Lok and Dr Pamela Tan from the Department of Bioengineering at NUS Faculty of Engineering, and Associate Professor Saminathan Suresh Nathan from the Department of Orthopaedic Surgery at the NUS Yong Loo Lin School of Medicine, who carried out their study using osteosarcoma, which is the most prevalent form of paediatric primary bone cancer.

Reconstructing tumours in the laboratory has been a hot topic for research as current methods of testing have not been sufficient to yield concrete results.

Dr Tan, who has been researching on the 3-D model for her PhD thesis, said: "Despite the urgent need to develop cancer therapeutics, little progress has been made due to the lack of good pre-clinical drug testing models. Current laboratory drug testing methods yield results that differ largely from animal testing because of the use of 2-D cell culture systems which cannot replicate the 3-D properties of the tumour tissue."

In in-vitro testing, cell culture systems are largely 2-D, hence, lack the structural features of the 3-D microenvironment. On the other hand, it is not feasible to carry out large-scale molecular biology research using in-vivo experiments. Furthermore, society has become increasingly concerned about the use of animals in experimentation.

Prof Goh said that tissue engineering, a major focus of study at the Department of Bioengineering, can help bridge these gaps, thereby establishing a more physiological 3-D in-vitro model. The team made use of techniques from tissue engineering to fabricate the 3-D tumour model and reconstructed the tumour tissue into factors and cell types in order to form a clinically relevant tumour.

The team decided to use silk to fabricate the scaffolds onto which the osteosarcoma cells were grown because it has been demonstrated to have excellent properties for cell attachment and growth.

Their 3-D tumour construct gives results that are much closer to those obtained from in-vivo studies, as compared to 2-D in-vitro studies. When chemotherapeutic drugs (which target aggressively growing cells) were tested on the 3-D tumour constructs, their effectiveness in killing cancer cells was greatly reduced, compared to testing the same drugs using the standard 2-D system. Moreover, the therapeutic doses found using the 3-D tumour constructs was within those measured in mice, indicating that the constructs have the potential to help bridge the gap between laboratory and animal testing, in order to improve the yield and quality of chemotherapeutic drug screening.

This is also the first time that a realistic 3-D tumour has been constructed in a laboratory using silk scaffolds in a pressurised bioreactor. Their 3-D bioreactor tumour model was able to express markers that indicate the ability of a tumour to initiate blood vessel growth at levels almost identical to that of the mouse model. The tumour constructs also responded to drugs that prevent blood vessel formation in a manner similar to that observed clinically.

"Our model also makes it possible to study how tumour cells interact with cells of the surrounding tissue, which results in more aggressive tumour behaviour," added Dr Tan.

The team has been developing the concept of the tumour microenvironment as an important determinant of tumour behaviour over the last 10 years.

Said Assoc Prof Nathan, "Dr Tan's recent contribution has shed remarkable insight into mechanisms of angiogenesis that were previously taken for granted and may now have to be re-addressed. Clinically this will have significant bearing on other drugs as well."

"We will in future be expanding our findings to other cancers and incorporating other aspects of the tumour microenvironment like oxygen levels within the system to ultimately create a platform for testing that could save much in downstream applications of experimental drugs," he added.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_technology/~3/j2xruZ4bzBI/130620071446.htm

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Source: http://today.msnbc.msn.com/id/3208047/device/rss/rss.xml

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Lavrov: Russian rebels will pose no risk at Sochi

ST. PETERSBURG, Russia (AP) ? Security agencies will make sure Russians fighting alongside rebels in Syria don't pose a threat to the 2014 Winter Games in Sochi, the foreign minister said Friday.

Sergey Lavrov said in an interview that the potential threat of them coming home to launch attacks "would be taken into account very seriously."

Lavrov said Moscow and Washington will cooperate on ensuring security for the Sochi Olympics, "making sure that the potentials of respective services and agencies of Russia and the United States are brought together to make the preparations more efficient."

He refused to elaborate on what specific steps will be taken.

Some observers have voiced concern that Islamic militants from Russia who have fought together with Syrian rebels could return home and try to take revenge against Russia for its support of Syrian President Bashar Assad. The chief of Russia's top security agency has said that about 200 Russians have joined the Syrian rebels, and acknowledged they could be a threat when they return.

Lavrov said nationals of European countries also have joined the rebels in Syria, and may pose a similar challenge to their home countries.

"This is not only relevant in the context of the Olympics, it's also relevant in the context of day-to-day life of entire Europe, the United States and other countries," he told The Associated Press and the Bloomberg news agency. "When this war is over ... these guys wouldn't be busy and they might look for some engagement" in the countries where they are citizens.

Russian officials have said that they have taken all necessary precautions to ensure the 2014 Winter Games in the Black Sea resort of Sochi will be "the safest Olympics in history." But security experts have pointed at an Islamic insurgency across the North Caucasus mountains that tower over Sochi, saying it could put President Vladimir Putin's pet project at risk.

The elder of the two ethnic Chechen brothers from Russia who are accused of staging the Boston Marathon bombings spent six months last year in the restive Russian province of Dagestan, which lies about 500 kilometers (300 miles) east of Sochi. Russian investigators have been trying to determine whether he had contact with local Islamic militants.

Dagestan has become the epicenter of Islamic insurgency that has destabilized the North Caucasus, with rebels mounting daily attacks on police and other officials.

Lavrov sought to downplay the threat posed by militants in the Caucasus. "Terrorist attacks happen, they aren't as numerous as before, and the Russian security services are becoming much more efficient in not only fighting the terrorists but also in preventing terrorist attacks," he said.

Source: http://news.yahoo.com/lavrov-russian-rebels-pose-no-risk-sochi-181451831.html

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Tuesday, June 18, 2013

Adobe's Q2 Earnings Beat Street With $1.011B In Revenue, $0.36 EPS, 700K Paying Creative Cloud Subscribers

adobe-logoAdobe just reported earnings for its second financial quarter of 2013. The company reported revenue of $1.011 billion and non-GAAP operating income of $247.3 for an earnings per share of $0.36 (though diluted GAAP earnings were only $0.15). That's a little bit better than most analysts expected, especially with respect to the company's earnings per share.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Hv9VjuMwoWk/

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